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A drug that was approved by U.S. regulators more than 70 years ago may help protect against two major COVID-19 symptoms, according to a new study.
Disulfiram, approved to treat alcoholism, protected rodents infected with COVID-19 from lung injury in the preclinical study done by researchers at Weill Cornell Medicine and Cold Spring Harbor Laboratory.
Certain white blood cells called neutrophils form inside some people suffering from COVID-19, damaging the lungs. No drugs have yet been found to prevent this from happening, researchers said.
Disulfiram, though, dramatically reduced the formation of neutrophil extracellular traps (NET), which cause fluid to accumulate in the lungs and sometimes lead to blood clots.
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