Vaccinated at Higher Risk of Serious Adverse Events: Reanalysis of Original Trial Data

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A secondary analysis of the data from the original clinical trials for the Pfizer and Moderna COVID-19 vaccines has found that the vaccinated arms were at higher risk of serious adverse events than the placebo arms.

Pfizer trial participants who received a vaccine were 36 percent more at risk of a serious adverse event, while Moderna trial participants who received a vaccine were six percent more at risk, according to the analysis, which was published after peer review in the journal Vaccine on Aug. 31.

Severe adverse events were defined as events that resulted in serious conditions such as death, inpatient hospitalization, and persistent disability.

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